American ASF vaccine works through oronasal route


Vincent ter Beek, Pig Progress

May 4, 2021   


An ASF vaccine that is under development in the United States has also been tested successfully when being provided through the oronasal route. The announcement offers hope for those countries having ASF in wild boar populations.


The vaccine candidate has been under development for years at the Plum Island Animal Disease Center, part of the Agricultural Research Service (ARS), which in turn belongs to the US Department of Agriculture (USDA). The vaccine candidate revolves around the deletion of the gene I177L from a highly virulent ASFv strain from the country Georgia (ASFv-G). Hence, the official name of the vaccine candidate is “ASFV-G-ΔI177L.”


Many test for ASF vaccine candidate


Between development and marketing, however, there are a wide range of tests required. The latest publication in a special edition of the peer-reviewed title Vaccines, is one of the steps of the vaccine development. Especially for wild boar, intramuscular vaccination is not an option, but it can be administered through feed when it is deposited for them in forests.


In December 2019, the news broke that sterile immunity against ASFv was possible with this vaccine. Ever since the scientific evidence has grown that the researchers are on the right track with this vaccine candidate...


ASF candidate for the oronasal route


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